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| Web URL(s): | https://scisoc.confex.com/scisoc/2016am/webprogram/Paper99022.html
Last checked: 11/22/2016 |
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| Publication Type:
| Report |
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| Content Type: | Abstract or Summary only |
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| Author(s): | Jung, Geunhwa;
Sang, Hyunkyu;
Chang, Taehyun;
Popko, James T. Jr.;
Yamada, Toshihiko |
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| Author Affiliation: | Jung: University of Massachusetts-Amherst, Amherst, MA; Sang: tockbridge School of Agriculture, University of Massachusetts-Amherst, Amherst, MA; Chang: School of Ecology & Environmental System, Kyungpook National University, Sangju, Korea, The Republic of; Popko: Stockbridge School of Agriculture, University of Massachusetts Amherst, Amherst, MA; Yamada: Field Science Center for Northern Biosphere, Hokkaido University, Sapporo, Japan |
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| Title: | Occurrence and mechanisms of multidrug resistance in Sclerotinia homoeocarpa |
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| Section: | Turfgrass management: Diseases/insects
Other records with the "Turfgrass management: Diseases/insects" Section
C05 turfgrass science
Other records with the "C05 turfgrass science" Section
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| Meeting Info.: | Phoenix, Arizona: November 6-9, 2016 |
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| Source: | ASA, CSSA and SSSA International Annual Meetings. 2016, p. 99022. |
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| Publishing Information: | [Milwaukee, Wisconsin]: [American Society of Agronomy and the Entomological Society of America] |
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| # of Pages: | 1 |
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| Keywords: | TIC Keywords: Cross-resistance; Fungicide resistance; Genetic analysis; Mechanism of resistance; Sclerotinia homoeocarpa; Transcription factors
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| Abstract/Contents: | "Dollar spot, the most economically significant turfgrass disease, is caused by the sterile ascomycete fungus Sclerotinia homoeocarpa. Repeated fungicide applications are required throughout the growing season to maintain high turf quality on golf courses. However, fungicide resistance has developed in at least three fungicide classes in the United States. Cross-resistance and multiple-resistance have been documented in S. homoeocarpa. Recently multidrug resistance was conferred by resistance to multiple chemistries using the same xenobiotic detoxification mechanisms and is becoming increasingly problematic in both plant and human pathogenic fungi. Our recent studies suggest that overexpression of ATP-binding cassette (ABC) efflux transporters and cytochrome P450 monooxygenases play in a significant role in multidrug resistance through various detoxification pathways. Furthermore, a novel fungal specific transcription factor regulates these xenobiotic detoxification genes/proteins and has been genetically characterized in S. homoeocarpa. In addition, a gain of function mutation in the transcription factor gives constitutive overexpression of the detoxification genes/proteins resulting in resistance to xenobiotic compounds. Current advances in understanding the genetic mechanisms of xenobiotic detoxification in S. homoeocarpa using functional genomic and genetic techniques such as RNA-seq, quantitative RT-PCR, and knockout and overexpressed mutants will be discussed." |
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| Language: | English |
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| References: | 0 |
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| Note: | This item is an abstract only!
"243-7" |
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| ASA/CSSA/SSSA Citation (Crop Science-Like - may be incomplete):
Jung, G., H. Sang, T. Chang, J. T. Jr. Popko, and T. Yamada. 2016. Occurrence and mechanisms of multidrug resistance in Sclerotinia homoeocarpa. Agron. Abr. p. 99022. |
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Last checked: 11/22/2016 |
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