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| Web URL(s): | http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1096-9063(199804)52:4<343::AID-PS726>3.0.CO;2-G/epdf
Last checked: 10/07/2015
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| Publication Type:
| Refereed |
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| Author(s): | Nezu, Yukio;
Wada, Nobuhide;
Yoshida, Fumitaka;
Miyazawa, Takeshige;
Shimizu, Tsutomu;
Fujita, Toshio |
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| Author Affiliation: | KI Chemical Research Institute CO., Ltd,; Life Science Research Institute, Kumiai Chemical CO., Ltd,; Department of Agricultural Chemistry; Japan |
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| Title: | Dimethoxypyrimidines as novel herbicides. Part 4. Quantitative structure-activity relationships of dimithoxypyrimidinyl(thio)salicylic acids |
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| Source: | Pesticide Science. Vol. 52, No. 4, April 1998, p. 343-353. |
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| Publishing Information: | London : Society of Chemical Industry |
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| # of Pages: | 11 |
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| Keywords: | TIC Keywords: Herbicides; Enzyme activity; Echinochloa crusgalli; Polygonum convolvulus; Broadleaf weed control; Experimental products; Mode of action; Models
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| Abstract/Contents: | "The activity of a number of O-(4,6-dimethoxypyrimidin-2-yl) salicylic acids and their thio analogs inhibiting acetolactate synthase (ALS) preparation was measured. The effects of substituents on the salicylic-benzene ring on the inhibitory activity were analyzed quantitatively with physicochemical substituent parameters. For 6-substituted (thio)salicylic acids, the activity was shown to vary parabolically with the 'intramolecular' steric parameter (E^D[s). In addition, the higher steric dimension of substituents in terms of the STERIMOL width or length parameter lowered the activity. The field-inductive electron-withdrawing property of the 6-substitutes in terms of the Swain-Lupton-Hansch F was favorable for the activity of salicylic acid series. In 5-substituted salicylic acids, the activity was increased by electron-donating substituents with smaller size. The relationships between ALS inhibitory and herbicidal activities were also analyzed with some weed species. Both pre- and post-emergence activities against barnyard grass, Echinochloa crus-galli, were linearly related to the ALS inhibitory activity after allowing for the hydrophobic factor that may contribute to the transport processes. Those against two broad-leaved weed species, Polygonum convolvulus and Abutilon theophrasti were linearly related to the in-vitro activity with no significant participation of the hydrophobic factor." |
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| Language: | English |
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| References: | 27 |
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| Note: | Tables
Figures |
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| ASA/CSSA/SSSA Citation (Crop Science-Like - may be incomplete):
Nezu, Y., N. Wada, F. Yoshida, T. Miyazawa, T. Shimizu, and T. Fujita. 1998. Dimethoxypyrimidines as novel herbicides. Part 4. Quantitative structure-activity relationships of dimithoxypyrimidinyl(thio)salicylic acids. Pest Manage. Sci. 52(4):p. 343-353. |
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| Web URL(s):
http://onlinelibrary.wiley.com/doi/10.1002/(SICI)1096-9063(199804)52:4<343::AID-PS726>3.0.CO;2-G/epdf
Last checked: 10/07/2015
Requires: PDF Reader
Access conditions: Item is within a limited-access website |
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MSU catalog number: SB 951 .A1 P45 |
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