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| Web URL(s): | http://apsjournals.apsnet.org/doi/pdf/10.1094/PHYTO.2000.90.6.S1#page=70
Last checked: 10/16/2015
Requires: PDF Reader
Notes: Item is within a single large file |
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| Publication Type:
| Report |
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| Content Type: | Abstract or Summary only |
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| Author(s): | Schnabel, G.;
Jones, A. L.;
Kuo, Min-Hao |
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| Author Affiliation: | Schnabel and Jones: Department of Botany and Plant Pathology; and Kuo: Department of Biochemistry, Michigan State University, East Lansing, MI |
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| Title: | Isolation and characterization of two novel drug efflux pumps from Venturia inaequalis |
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| Section: | Abstracts submitted for presentation at the 2000 APS annual meeting
Other records with the "Abstracts submitted for presentation at the 2000 APS annual meeting" Section
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| Meeting Info.: | APS Annual Meeting, New Orleans, LA, August 12-16, 2000 |
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| Source: | Phytopathology. Vol. 90, No. 6, June 2000, p. S70. |
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| Publishing Information: | St. Paul, MN: American Phytopathological Society |
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| # of Pages: | 1 |
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| Keywords: | TIC Keywords: Venturia inaequalis; Fungicide resistance; Genes; Simple sequence repeats; Aspergillus nidulans; Gene expression
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| Abstract/Contents: | "We isolated and sequenced 2 genes (ViABC1 and ViABC2) from V. inaequalis, encoding drug efflux pumps belonging to the ATP-binding casette (ABC) transporter superfamily and investigated their role in fungicide resistance. ViABC1 contains 6 introns and encodes a protein of 1552 amino acids (aa). ViABC2 contains 3 introns and encodes a protein of 1490 aa. The aa sequence of the 2 ATP-binding cassettes and the 2 transmembrane domains of both genes were aligned with each other and with those from ABC transporters from other fungi. Highest sequence similarity to ViABC1 was found for AtrA from Aspergillus nidulans (64.5%). Highest sequence similarity to ViABC2 was found for AtrB from Botrytis cinerea (38.5%). Northern analysis revealed constitutive high expression of ViABC1 and ViABC2 in some myclobutanil resistant strains but not in sensitive strains, suggesting a possible role in fungicide resistance. A functional analysis of both genes is currently being investigated in yeast." |
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| Language: | English |
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| References: | 0 |
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| Note: | This item is an abstract only! |
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| ASA/CSSA/SSSA Citation (Crop Science-Like - may be incomplete):
Schnabel, G., A. L. Jones, and M.-H. Kuo. 2000. Isolation and characterization of two novel drug efflux pumps from Venturia inaequalis. Phytopathology. 90(6):p. S70. |
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| Web URL(s):
http://apsjournals.apsnet.org/doi/pdf/10.1094/PHYTO.2000.90.6.S1#page=70
Last checked: 10/16/2015
Requires: PDF Reader
Notes: Item is within a single large file |
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MSU catalog number: SB 599 .P48 |
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