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| Web URL(s): | http://onlinelibrary.wiley.com/doi/10.1002/ps.2780450202/epdf
Last checked: 10/07/2015
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| Publication Type:
| Refereed |
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| Author(s): | McClintock, J. Thomas;
Schaffer, Cindy R.;
Sjoblad, Roy D. |
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| Author Affiliation: | US Environmental Protection Agency, Office of Pesticide Programs, Biopesticides and Pollution Prevention Division, Washington, DC 20460, USA |
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| Title: | A comparative review of the mammalian toxicity of bacillus thuringiensis-based pesticides |
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| Section: | Review
Other records with the "Review" Section
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| Source: | Pesticide Science. Vol. 45, No. 2, October 1995, p. 95-105. |
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| Publishing Information: | London : Society of Chemical Industry |
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| # of Pages: | 11 |
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| Keywords: | TIC Keywords: Bacillus thuringiensis; Mammalian toxicity; Pesticide safety; Biological pest control
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| Abstract/Contents: | "The extensive mammalian toxicity studies performed to support the safety of Bacillus thuringiensis-containing pesticides clearly demonstrate that the tested isolates are not toxic or pathogenic. Toxicity studies submitted to the US Environmental Protection Agency to support the registration of B. thuringiensis subspecies have failed to show any significant adverse effects in body weight gain, clinical observations, or upon necropsy. Infectivity/ pathogenicity studies have shown that the intact rodent immune system responds as expected to eliminateB. thuringiensis gradually from the body after oral, pulmonary or intravenous challenge. Similar clearance patterns were observed with B. subtilis and B. sphaericus, which also were non-toxic to test animals. The results also indicate that the currently used protocols for toxicity/ pathogenicity evaluations of microorganisms in laboratory animals have provided useful and necessary information for risk assessment. The study results raise the issue, however, of whether some reduced set of toxicity/ pathogenicity studies could be required for new B. thuringiensis isolates of already registered subspecies, and whether this reduced data set would apply to subspecies not yet registered as pesticidal active ingredients." |
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| Language: | English |
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| References: | 52 |
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| Note: | Figures
Tables |
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| ASA/CSSA/SSSA Citation (Crop Science-Like - may be incomplete):
McClintock, J. T., C. R. Schaffer, and R. D. Sjoblad. 1995. A comparative review of the mammalian toxicity of bacillus thuringiensis-based pesticides. Pest Manage. Sci. 45(2):p. 95-105. |
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| Web URL(s):
http://onlinelibrary.wiley.com/doi/10.1002/ps.2780450202/epdf
Last checked: 10/07/2015
Requires: PDF Reader
Access conditions: Item is within a limited-access website |
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MSU catalog number: SB 951 .A1 P45 |
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